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Consumer Affairs

Coffee May Protect Against Endometrial Cancer

More antioxidants that most fruits and vegetables


PhotoIn the 1970s a series of studies suggested drinking coffee could have harmful heath effects. This decade, it seems study after study finds some health benefit from coffee.

Researchers writing in a journal of he American Association for Cancer Research say long-term coffee consumption may be associated with a reduced risk for endometrial cancer, the most common gynecologic cancers in the United States, with over 35,000 women diagnosed each year.

Edward Giovannucci, professor of nutrition and epidemiology at the Harvard School of Public Health, said coffee is emerging as a protective agent in cancers that are linked to obesity, estrogen and insulin.

Protects against diabetes

“Coffee has already been shown to be protective against diabetes due to its effect on insulin,” said Giovannucci, a senior researcher on the study. “So we hypothesized that we’d see a reduction in some cancers as well.”

Giovannucci, along with Youjin Je, a doctoral candidate in his lab, and colleagues observed cumulative coffee intake in relation to endometrial cancer in 67,470 women who enrolled in the Nurses’ Health Study.

During the course of 26 years of follow-up, researchers documented 672 cases of endometrial cancer.

Drinking more than four cups of coffee per day was linked with a 25 percent reduced risk for endometrial cancer. Drinking between two and three cups per day was linked with a 7 percent reduced risk.

It's not the caffeine

A similar link was seen in decaffeinated coffee, where drinking more than two cups per day was linked with a 22 percent reduced risk for endometrial cancer.

Giovannucci said he hopes this study will lead to further inquiries about the effect of coffee on cancer because in this and similar studies, coffee intake is self-selected and not randomized.

“Coffee has long been linked with smoking, and if you drink coffee and smoke, the positive effects of coffee are going to be more than outweighed by the negative effects of smoking,” said Giovannucci. “However, laboratory testing has found that coffee has much more antioxidants than most vegetables and fruits.”


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