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Researchers “A Step Closer” To Alzheimer’s Cure

July 23, 2007

• Dementia Linked To Obesity • Studies Find Link Between Diabetes and Alzheimer's • Lifestyle Linked to Alzheimer's Onset • Pot Belly in Middle Age Linked to Alzheimer's • 10 Million Boomers Face Alzheimer's • Alzheimer's Risk Higher in Victims' Children • Fast-Acting Alzheimer's Therapy Excites Researchers • Too Much Sugar May Increase Alzheimer’s Risk • Beta Carotene May Slow Memory Loss • Promising Alzheimer’s Discovery Reported • Misconceptions About Alzheimer's Vary Among Races • Mediterranean Diet May Extend Alzheimer’s Patients’ Lives • Researchers Link Smoking To Dementia • Caffeine May Keep Dementia At Bay In Women • Alzheimer’s Drug Seen As “Safe, Effective” • Researchers “A Step Closer” To Alzheimer’s Cure • FDA Approves Alzheimer’s Patch • Scientists Raise Hopes For Alzheimer's Vaccine • Researchers Hopeful About New Alzheimer’s Therapy • Blood Pressure Drugs May Provide Alzheimer’s Protection • Progress Toward Early Alzheimer's Diagnosis Reported • Alzheimer's Cases Up 10% In 5 Years • Loneliness Linked to Dementia • Gene Changes Identified in Alzheimer's • Mental Exercise May Help Seniors • Rote Learning Improves Memory in Seniors • Vegetables May Slow Memory Loss • Cabernet Sauvignon May Reduce Alzheimer's Risk • Fruit Juice May Reduce Alzheimer's Risk • Skin Test May Detect Alzheimer's Disease • Exercise May Prevent Dementia-Like Illnesses • An Apple A Day May Improve Memory • New Drug Reverses Alzheimer's Damage, Australian Researchers Report • Diabetes Drug May Help Treat Alzheimer's • For Women, Weight Loss May Precede Dementia • Researchers "Closer" To Preventing Alzheimer's • Statins Help Memory in Older Women • Study Links Healthy Diet To Reduced Alzheimer's Risk • Tea May Help Combat Alzheimer's • Education May Accelerate Alzheimer's Effects • Alzheimer's Found to be Mostly Genetic • Exercise May Reduce Risk of Dementia in Older People • Researchers Find DNA Link to Alzheimer's • Brain Scan, Fluid Analysis May Help Predict Alzheimer's • Eating Fish Associated With Slower Cognitive Decline • Word Recall An Alzheimer' s Tip-Off? • Interrupted Alzheimer's Trial Produced Promising Results • Gene Therapy May Offer Hope For Alzheimer's Patients • Alzheimer's Researchers Reverse Memory Loss in Mice • Alzheimer's Disease Reveals Itself Earlier, Study Finds

British and U.S. health researchers have developed a drug one Alzheimer’s disease expert says would be “the Holy Grail” if it lives up to its billing – stopping, and even curing, Alzheimer’s disease.

The research team, based at the University of Saint Andrews in the UK, has reportedly developed compounds that can block a nerve cell interaction long associated with development of the memory-destroying disease.

Because of the preliminary results, the Alzheimer’s Research Trust is funding another three years of work on the project.

Trust chief executive Rebecca Wood says the breakthrough is exciting and holds enormous promise. The number of people afflicted with Alzheimer’s is projected to double in the next decade are life spans increase and the baby boom generation ages.

Alzheimer's is currently a non-reversible degenerative brain disease, caused by a build-up of plaque in blood vessels serving the brain. The plaque is caused by amyloid protein, which compounds the damage as it interacts with an enzyme called Amyloid Beta Alcohol Dehydrogenase, releasing toxic substances that kill brain cells.

The last year has brought other promising reports of progress against Alzheimer’s.

In July 2006 a study directed by Mount Sinai School of Medicine identified a faulty molecule in the brain found in cases of mild cognitive impairment (MCI). Researchers said this faulty molecule may be responsible for the progression of MCI to mild Alzheimer's disease.

According to the American Health Assistance Foundation, more than 4.5 million people in the United States live with the disease and more than 26 million people are affected worldwide.

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